General Western Blot Reagents
Abcam Salmeterol x inafoate, beta2 adrenoceptor agonist, 10MG
MW 603.7 Da, Purity >96%. Selective, long acting β2 adrenoceptor agonist. Inhibits release of histamine, leukotrienes, prostaglandin D2 and GM-CSF in concentration-dependent manner. Active *in vitro* and *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Prostratin, PKC activator, 500UG
MW 390.48 g/mol. PKC activator; reactivates HIV-1 latency (IC₅₀ = ~0.5 μM) by PKC dependent NF-κB activation. Downregulates expression of HIV-1 receptor CD4 and its co-receptors CXCR4 and CCR5 in vitro. Non-tumor promoting.
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc 4CN Plus Chromogenic Substrate, 2 Bottles
4CN Plus Chromogenic Substrate, 2 Bottles
Abcam Nifedipine, L-type Ca2+ channel blocker, 1G
MW 346.3 Da, Purity >99%. L-type Ca2+ channel blocker. Potent, long-acting vasodilator. Also shown to inhibit vascular inflammation.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tenovin-1, p53 Activator, 10MG
MW 369.48 g/mol, Purity >98%. p53 Activator. Protects p53 from MDM2 mediated degradation through SirT1 inhibition. Inhibits downstream histone acetylation, activates p21CIP/WAF1. Potent antiproliferative effects in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Olanzapine, 5-HT, dopamine, histamine and muscarinic antagonist, 50MG
MW 312.43 g/mol, Purity >99%. 5-HT and D₂ antagonist (Ki values are 4 (5-HT₂A), 11 (5-HT₂C) and 57 (5-HT₃), 31 (D₁), 11 (D₂) and 27 nM (D₄)). Additionally, displays activity at: M₁, M₂, M₃, M₄, H₁, α₁ and α₂ receptors (Ki are 1.9 at (M₁), 18 (M₂), 25 (M₃), 13 (M₄), 19 (α₁) and 7 nM (α₂)). Atypical antipsychotic. Displays anxiolytic activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Honokiol, anti-inflammatory and chemotherapeutic agent, 10MG
MW 266.34 g/mol, Purity >98%. Potent scavenger of reactive oxygen species with antiangiogenic, antitumor and anti-inflammatory properties. Mechanisms of action include inhibition of ras signalling and activation of the mitochondrial transistion pore via cyclophilin D induction. Inhibits NF-κB signaling, upstream of VEGF. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Honokiol, anti-inflammatory and chemotherapeutic agent, 25MG
MW 266.34 g/mol, Purity >98%. Potent scavenger of reactive oxygen species with antiangiogenic, antitumor and anti-inflammatory properties. Mechanisms of action include inhibition of ras signalling and activation of the mitochondrial transistion pore via cyclophilin D induction. Inhibits NF-κB signaling, upstream of VEGF. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Venlafa x ine hydrochloride, Serotonin-norepinephrine reuptake inhibitor, 50MG
MW 313.87 g/mol, Purity >99%. Serotonin-norepinephrine reuptake inhibitor. Ki values are 82 and 2480 nM for SERT and NET, respectively. Displays 30-fold higher affinity for SERT than NET in vitro. Antidepressant.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc Mouse Cytochrome P450 2E1 CYP
Mouse Cytochrome P450 2E1 (CYP2E1) ELISA kit from CUSABIO Detection Range 39 pg/mL-2500 pg/mL Sensitivity 9 75 pg/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
Abcam CAY10585, HIF-1alpha inhibitor, 25MG
MW 435.5 Da, Purity >97%. HIF-1α inhibitor (IC₅₀ values are 2.6 and 0.7 μM for Hep3B and AGS cell lines respectively). Suppresses transcription of HIF-1 target genes VEGF and erythropoietin at 10 μM. Attenuates hypoxia-induced ANP secretion. Blunts BMP9-induced osteogenic signaling in MSCs.
The product is subject to the following: Abcam Restricted Use Statement
Abcam gamma-Tocotrienol, Form of vitamin E, 25MG
MW 410.6 Da, Purity >98%. Form of vitamin E. Antioxidant agent. Tocotrienol α (ab144451), β (ab145176) and δ (ab144449) analog. Induces apoptosis in cancer cells. Shows antitumor and antihypertensive effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam p53 Transcription Factor Assay Kit (Colorimetric)
p53 Transcription Factor Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam BTBCT, Europium beta-diketone chelate, 5MG
MW 604.9 Da, Purity >95%. Europium β-diketone chelate. Provides 8 times improved detection sensitivity compared to BHHCT-(Asc5314
The product is subject to the following: Abcam Restricted Use Statement
Abcam 6-IAF (6-Iodoacetamidofluorescein), Thiol-reactive fluorescent label, 250MG
MW 515.3 Da, Purity >95%. Thiol-reactive fluorescent label. Acts as an acceptor fluorophore in FRET studies with excitation and emission maxima of 347 and 530 nm respectively. 6-IATR (ab145010) derivative. Labels actin, microtubule-associated proteins and histones.
The product is subject to the following: Abcam Restricted Use Statement